Loss of CDKN1A mRNA and Protein Expression Are Independent Predictors of Poor Outcome in Chromophobe Renal Cell Carcinoma Patients

Loss of CDKN1A mRNA and Protein Expression Are Independent Predictors of Poor Outcome in Chromophobe Renal Cell Carcinoma Patients

Chromophobe renal cell carcinoma (chRCC) patients have good prognosis. Only 5%−10% patients die of metastatic disease after tumorectomy, but tumor progression cannot be predicted by histopathological parameters alone. chRCC are characterized by losses of many chromosomes, whereas gene muta...

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Bibliographic Details
Main Authors: Riuko Ohashi, Silvia Angori, Aashil A. Batavia, Niels J. Rupp, Yoichi Ajioka, Peter Schraml, Holger Moch
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
chromophobe renal cell carcinoma
copy number loss
cdkn1a expression
patient survival
prognosis
Online Access:https://www.mdpi.com/2072-6694/12/2/465

Internet

https://www.mdpi.com/2072-6694/12/2/465

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