Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection

Quasispecies variant of pre-S/S gene in HBV-related hepatocellular carcinoma with HBs antigen positive and occult infection

Abstract Background Hepatocellular carcinoma (HCC) can develop in patients who are negative for the hepatitis B surface antigen (HBsAg) in serum but positive for hepatitis B virus (HBV) DNA in the liver, referred to as occult HBV infection (OBI). Previous reports showed that HBV variants in OBI-rela...

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Bibliographic Details
Main Authors: Yuri Hatazawa, Yoshihiko Yano, Rina Okada, Toshihito Tanahashi, Hiroki Hayashi, Hirotaka Hirano, Akihiro Minami, Yuki Kawano, Motofumi Tanaka, Takumi Fukumoto, Yoshiki Murakami, Masaru Yoshida, Yoshitake Hayashi
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Infectious Agents and Cancer
Subjects:
HBV
Pre-S/S
Quasispecies
Occult
HCC
Ultra-deep sequencing
Online Access:http://link.springer.com/article/10.1186/s13027-018-0179-4

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http://link.springer.com/article/10.1186/s13027-018-0179-4

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