Long Term Osmotic Mini Pump Treatment with Alpha-MSH Improves Myocardial Function in Zucker Diabetic Fatty Rats

Long Term Osmotic Mini Pump Treatment with Alpha-MSH Improves Myocardial Function in Zucker Diabetic Fatty Rats

The present investigation evaluates the cardiovascular effects of the anorexigenic mediator alpha-melanocyte stimulating hormone (MSH), in a rat model of type 2 diabetes. Osmotic mini pumps delivering MSH or vehicle, for 6 weeks, were surgically implanted in Zucker Diabetic Fatty (ZDF) rats. Serum p...

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Bibliographic Details
Main Authors: Miklos Szokol, Daniel Priksz, Mariann Bombicz, Balazs Varga, Arpad Kovacs, Gabor Aron Fulop, Tamas Csipo, Aniko Posa, Attila Toth, Zoltan Papp, Zoltan Szilvassy, Bela Juhasz
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Molecules
Subjects:
alpha-melanocyte-stimulating hormone
echocardiography
isolated working heart
myocyte force
NADPH oxidase
Online Access:https://www.mdpi.com/1420-3049/22/10/1702

Internet

https://www.mdpi.com/1420-3049/22/10/1702

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