Effects of infection history on dengue virus infection and pathogenicity

Lack of knowledge of individual infection history hinders understanding of immunological interactions among DENV serotypes. Here, the authors introduce a framework to infer the relationship between unobserved infection history and subsequent infection and disease risk, and find complex dependencies.

Bibliographic Details
Main Authors: Tim K. Tsang, Samson L. Ghebremariam, Lionel Gresh, Aubree Gordon, M. Elizabeth Halloran, Leah C. Katzelnick, Diana Patricia Rojas, Guillermina Kuan, Angel Balmaseda, Jonathan Sugimoto, Eva Harris, Ira M. Longini, Yang Yang
Format: Article
Language:English
Published: Nature Publishing Group 2019-03-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-019-09193-y