Secreted protein acidic and rich in cysteine is a matrix scavenger chaperone.

Secreted Protein Acidic and Rich in Cysteine (SPARC) is one of the major non-structural proteins of the extracellular matrix (ECM) in remodeling tissues. The functional significance of SPARC is emphasized by its origin in the first multicellular organisms and its high degree of evolutionary conserva...

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Bibliographic Details
Main Authors: Alexandre Chlenski, Lisa J Guerrero, Helen R Salwen, Qiwei Yang, Yufeng Tian, Andres Morales La Madrid, Salida Mirzoeva, Patrice G Bouyer, David Xu, Matthew Walker, Susan L Cohn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21949685/?tool=EBI