Urinary biomarkers for early detection of platinum based drugs induced nephrotoxicity

Urinary biomarkers for early detection of platinum based drugs induced nephrotoxicity

Abstract Background Nephrotoxicity is a major hazard complicating the use of platinum based drugs (PBD), which can hinder using higher doses protocols to maximize the therapeutic gain. Shortage of serum creatinine level as an accurate biomarker for acute kidney injuries (AKI) necessitates searching...

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Bibliographic Details
Main Authors: Mostafa Abdelsalam, Ekramy Elmorsy, Hassan Abdelwahab, Osman Algohary, Mahmoud Naguib, Ahmed Abd El Wahab, Ahmed Eldeeb, Ehab Eltoraby, Adel Abdelsalam, Alaa Sabry, Mohamed El-Metwally, Mohamed Akl, Nahla Anber, Maysaa El Sayed Zaki, Fahad Almutairi, Tamer Mansour
Format: Article
Language:English
Published: BMC 2018-09-01
Series:BMC Nephrology
Subjects:
Platinum based drugs
Cisplatin
Oxaplatin
Urinary biomarkers
Nephrotoxicity
Online Access:http://link.springer.com/article/10.1186/s12882-018-1022-2

Internet

http://link.springer.com/article/10.1186/s12882-018-1022-2

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