Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

Intracellular amyloid and the neuronal origin of Alzheimer neuritic plaques

Genetic analysis of familial forms of Alzheimer's disease (AD) causally links the proteolytic processing of the amyloid precursor protein (APP) and AD. However, the specific type of amyloid and mechanisms of amyloid pathogenesis remain unclear. We conducted a detailed analysis of intracellular...

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Bibliographic Details
Main Authors: Anna Pensalfini, Ricardo Albay, III, Suhail Rasool, Jessica W. Wu, Asa Hatami, Hiromi Arai, Lawrence Margol, Saskia Milton, Wayne W. Poon, Maria M. Corrada, Claudia H. Kawas, Charles G. Glabe
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Neurobiology of Disease
Subjects:
Alzheimer
Intracellular amyloid
Nuclear pathology
Neuritic plaques
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114002125

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http://www.sciencedirect.com/science/article/pii/S0969996114002125

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