Image-Based Profiling of Synaptic Connectivity in Primary Neuronal Cell Culture

Image-Based Profiling of Synaptic Connectivity in Primary Neuronal Cell Culture

Neurological disorders display a broad spectrum of clinical manifestations. Yet, at the cellular level, virtually all these diseases converge into a common phenotype of dysregulated synaptic connectivity. In dementia, synapse dysfunction precedes neurodegeneration and cognitive impairment by several...

Full description

Bibliographic Details
Main Authors: Peter Verstraelen, Michiel Van Dyck, Marlies Verschuuren, Nachiket D. Kashikar, Rony Nuydens, Jean-Pierre Timmermans, Winnok H. De Vos
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Neuroscience
Subjects:
primary neuronal culture
synapse
dendritic spine
image analysis
morphofunctional connectivity
fluorescent labeling
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2018.00389/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2018.00389/full

Similar Items