Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation

Many developing neurons transition through a multi-polar state with many competing neurites before assuming a unipolar state with one axon and multiple dendrites. Hallmarks of the multi-polar state are large fluctuations in microtubule-based transport into and outgrowth of different neurites, althou...

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Bibliographic Details
Main Authors: Amy M Winans, Sean R Collins, Tobias Meyer
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-02-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/12387