Prenatal Dexamethasone and Postnatal High-Fat Diet Decrease Interferon Gamma Production through an Age-Dependent Histone Modification in Male Sprague-Dawley Rats

Prenatal Dexamethasone and Postnatal High-Fat Diet Decrease Interferon Gamma Production through an Age-Dependent Histone Modification in Male Sprague-Dawley Rats

Overexposure to prenatal glucocorticoid (GC) disturbs hypothalamic-pituitary-adrenocortical axis-associated neuroendocrine metabolism and susceptibility to metabolic syndrome. A high-fat (HF) diet is a major environmental factor that can cause metabolic syndrome. We aimed to investigate whether pren...

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Bibliographic Details
Main Authors: Hong-Ren Yu, You-Lin Tain, Jiunn-Ming Sheen, Mao-Meng Tiao, Chih-Cheng Chen, Ho-Chang Kuo, Pi-Lien Hung, Kai-Sheng Hsieh, Li-Tung Huang
Format: Article
Language:English
Published: MDPI AG 2016-09-01
Series:International Journal of Molecular Sciences
Subjects:
prenatal glucocorticoid
high-fat diet
IFN-γ
histone modification
age-dependent
Online Access:http://www.mdpi.com/1422-0067/17/10/1610

Internet

http://www.mdpi.com/1422-0067/17/10/1610

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