Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

Inositol 1,4,5-trisphosphate receptors (IP3Rs) are a family of intracellular Ca2+ release channels located on the ER membrane, which in mammals consist of 3 different subtypes (IP3R1, IP3R2, and IP3R3) encoded by 3 genes, Itpr1, Itpr2, and Itpr3, respectively. Studies utilizing genetic knockout mous...

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Bibliographic Details
Main Authors: Feili Yang, Lei Huang, Alexandria Tso, Hong Wang, Li Cui, Lizhu Lin, Xiaohong Wang, Mingming Ren, Xi Fang, Jie Liu, Zhen Han, Ju Chen, Kunfu Ouyang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-04-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008739

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https://doi.org/10.1371/journal.pgen.1008739

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