Relationship of CT-quantified emphysema, small airways disease and bronchial wall dimensions with physiological, inflammatory and infective measures in COPD

Abstract Background COPD is a complex, heterogeneous disease characterised by progressive development of airflow limitation. Spirometry provides little information about key aspects of pathology and is poorly related to clinical outcome, so other tools are required to investigate the disease. We sou...

Full description

Bibliographic Details
Main Authors: Kristoffer Ostridge, Nicholas P. Williams, Viktoriya Kim, Stephen Harden, Simon Bourne, Stuart C. Clarke, Emmanuel Aris, Sonia Mesia-Vela, Jeanne-Marie Devaster, Andrew Tuck, Anthony Williams, Stephen Wootton, Karl J. Staples, Tom M. A. Wilkinson, on behalf of the AERIS Study Group
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Respiratory Research
Subjects:
CT
Online Access:http://link.springer.com/article/10.1186/s12931-018-0734-y