Construction of a High Titer Infectious HIV-1 Subtype C Proviral Clone from South Africa

Construction of a High Titer Infectious HIV-1 Subtype C Proviral Clone from South Africa

The Human Immunodeficiency Virus type 1 (HIV-1) subtype C is currently the predominant subtype worldwide. Cell culture studies of Sub-Saharan African subtype C proviral plasmids are hampered by the low replication capacity of the resulting viruses, although viral loads in subtype C infected patients...

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Bibliographic Details
Main Authors: Jochen Bodem, Stefanie Bock, Anita Schuch, Rebecca Moschall, Eva-Maria Schrom, Juliane Zahn, Christian Reuter, Graeme B. Jacobs, Thomas Kerkau, Axel Rethwilm, Susan Engelbrecht, Wolfgang Preiser
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:Viruses
Subjects:
HIV-1
subtype C
proviral plasmid
viral replication
resistance assays
Vpu
CD317
CD4
Online Access:http://www.mdpi.com/1999-4915/4/9/1830

Internet

http://www.mdpi.com/1999-4915/4/9/1830

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