Targeting TGF-β Signaling in Kidney Fibrosis
Renal fibrosis is the final common pathway of numerous progressive kidney diseases, and transforming growth factor-β (TGF-β) has an important role in tissue fibrosis by up-regulating matrix protein synthesis, inhibiting matrix degradation, and altering cell-cell interaction. Many s...
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Format: | Article |
Language: | English |
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MDPI AG
2018-08-01
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Series: | International Journal of Molecular Sciences |
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Online Access: | http://www.mdpi.com/1422-0067/19/9/2532 |