Measuring DNA content in live cells by fluorescence microscopy

Abstract Background Live-cell fluorescence microscopy (LCFM) is a powerful tool used to investigate cellular dynamics in real time. However, the capacity to simultaneously measure DNA content in cells being tracked over time remains challenged by dye-associated toxicities. The ability to measure DNA...

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Bibliographic Details
Main Authors: Cecil J. Gomes, Michael W. Harman, Sara M. Centuori, Charles W. Wolgemuth, Jesse D. Martinez
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Cell Division
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13008-018-0039-z