Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

Novel pandemic influenza A(H1N1) viruses are potently inhibited by DAS181, a sialidase fusion protein.

The recent emergence of a novel pandemic influenza A(H1N1) strain in humans exemplifies the rapid and unpredictable nature of influenza virus evolution and the need for effective therapeutics and vaccines to control such outbreaks. However, resistance to antivirals can be a formidable problem as evi...

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Bibliographic Details
Main Authors: Gallen B Triana-Baltzer, Larisa V Gubareva, John M Nicholls, Melissa B Pearce, Vasiliy P Mishin, Jessica A Belser, Li-Mei Chen, Renee W Y Chan, Michael C W Chan, Maria Hedlund, Jeffrey L Larson, Ronald B Moss, Jacqueline M Katz, Terrence M Tumpey, Fang Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770640?pdf=render

Internet

http://europepmc.org/articles/PMC2770640?pdf=render

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