Development and Characterization of Eudragit<sup>®</sup>-Based Electrospun Nanofibrous Mats and Their Formulation into Nanofiber Tablets for the Modified Release of Furosemide

Development and Characterization of Eudragit<sup>®</sup>-Based Electrospun Nanofibrous Mats and Their Formulation into Nanofiber Tablets for the Modified Release of Furosemide

Furosemide, a chloride channel blocker ordinarily used as a high-ceiling or loop diuretic, is practically insoluble in water and dilute acids. Due to its acidic nature, furosemide is mostly absorbed in the stomach and in the upper small intestine. Efforts have focused on the development of sustained...

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Bibliographic Details
Main Authors: Marilena Vlachou, Stefanos Kikionis, Angeliki Siamidi, Sotiria Kyriakou, Andrew Tsotinis, Efstathia Ioannou, Vassilios Roussis
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Pharmaceutics
Subjects:
furosemide
Eudragit<sup>®</sup>
electrospinning
nanofibers
tablets
modified release
Online Access:https://www.mdpi.com/1999-4923/11/9/480

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https://www.mdpi.com/1999-4923/11/9/480

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