A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer
<p>Abstract</p> <p>The pathways downstream of the epidermal growth factor receptor (EGFR) have often been implicated to play crucial roles in the development and progression of various cancer types. Different authors have proposed models in cell lines in which they study the modes...
Main Authors: | von der Heyde Silvia, Beissbarth Tim |
---|---|
Format: | Article |
Language: | English |
Published: |
BMC
2012-05-01
|
Series: | BMC Medicine |
Subjects: | |
Online Access: | http://www.biomedcentral.com/1741-7015/10/43 |
Similar Items
-
Phase I Study of Ficlatuzumab and Cetuximab in Cetuximab-Resistant, Recurrent/Metastatic Head and Neck Cancer
by: Julie E. Bauman, et al.
Published: (2020-06-01) -
The Role of Akt in Acquired Cetuximab Resistant Head and Neck Squamous Cell Carcinoma: An In Vitro Study on a Novel Combination Strategy
by: Hannah Zaryouh, et al.
Published: (2021-09-01) -
A Prospective Real-World Multi-Center Study to Evaluate Progression-Free and Overall Survival of Radiotherapy with Cetuximab and Platinum-Based Chemotherapy with Cetuximab in Locally Recurrent Head and Neck Cancer
by: Markus Hecht, et al.
Published: (2021-07-01) -
Interleukin-1 signaling contributes to the anti-tumor efficacy of Cetuximab in head and neck squamous cell carcinoma
by: Espinosa-Cotton, Madelyn
Published: (2018) -
Treatment response lowers tumor symptom burden in recurrent and/or metastatic head and neck cancer
by: Markus Hecht, et al.
Published: (2020-09-01)