scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy

scSensitiveGeneDefine: sensitive gene detection in single-cell RNA sequencing data by Shannon entropy

Abstract Background Single-cell RNA sequencing (scRNA-seq) is the most widely used technique to obtain gene expression profiles from complex tissues. Cell subsets and developmental states are often identified via differential gene expression patterns. Most of the single-cell tools utilized highly va...

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Bibliographic Details
Main Authors: Zechuan Chen, Zeruo Yang, Xiaojun Yuan, Xiaoming Zhang, Pei Hao
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Bioinformatics
Subjects:
Sensitive genes
Single-cell RNA sequencing
Stochastic gene expression
Unsupervised clustering
Online Access:https://doi.org/10.1186/s12859-021-04136-1

Internet

https://doi.org/10.1186/s12859-021-04136-1

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