The two PPX-GppA homologues from Mycobacterium tuberculosis have distinct biochemical activities.

Inorganic polyphosphate (poly-P), guanosine pentaphosphate (pppGpp) and guanosine tetraphosphate (ppGpp) are ubiquitous in bacteria. These molecules play a variety of important physiological roles associated with stress resistance, persistence, and virulence. In the bacterial pathogen Mycobacterium...

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Bibliographic Details
Main Authors: Mei Y Choi, Ying Wang, Leo L Y Wong, Bing-Tai Lu, Wen-Yang Chen, Jian-Dong Huang, Julian A Tanner, Rory M Watt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411833?pdf=render