The Role of Heat Shock Proteins in Antigen Cross Presentation
Heat shock proteins (HSP) are molecular chaperones that can bind tumor antigens (Ag) and mediate their uptake into antigen presenting cells (APC). HSP-antigen complexes are then directed towards the MHC class I pathway through antigen cross presentation as well as to the conventional class II pathwa...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-03-01
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| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00063/full |