Efficacy of Tasimelteon (HETLIOZ®) in the Treatment of Jet Lag Disorder Evaluated in an 8-h Phase Advance Model; a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Efficacy of Tasimelteon (HETLIOZ®) in the Treatment of Jet Lag Disorder Evaluated in an 8-h Phase Advance Model; a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Background: Most travelers experience Jet Lag Disorder (JLD) symptoms due to misalignment of their circadian rhythms with respect to the new time zone. We assessed the efficacy and safety of tasimelteon (HETLIOZ®) in healthy participants using a laboratory model of JLD induced by an 8-h phase advanc...

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Bibliographic Details
Main Authors: Christos M. Polymeropoulos, Michael A. Mohrman, Madison S. Keefe, Jennifer L. Brzezynski, Jingyuan Wang, Lydia S. Prokosch, Vasilios M. Polymeropoulos, Changfu Xiao, Gunther Birznieks, Mihael H. Polymeropoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neurology
Subjects:
jet lag disorder
circadian rhythm
tasimelteon
sleep
circadian
Hetlioz
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2020.00611/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2020.00611/full

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