Genistein Combined Polysaccharide (GCP) Can Inhibit Intracrine Androgen Synthesis in Prostate Cancer Cells

Genistein Combined Polysaccharide (GCP) Can Inhibit Intracrine Androgen Synthesis in Prostate Cancer Cells

Our group and others have previously shown that genistein combined polysaccharide (GCP), an aglycone isoflavone-rich extract with high bioavailability and low toxicity, can inhibit prostate cancer (CaP) cell growth and survival as well as androgen receptor (AR) activity. We now elucidate the mechani...

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Bibliographic Details
Main Authors: Neelu Batra, Anhao Sam, Tibebe Woldemariam, George Talbott, Ralph W. de Vere White, Paramita M. Ghosh, Nilesh W. Gaikwad, Simeon O. Kotchoni, Ruth L. Vinall
Format: Article
Language:English
Published: MDPI AG 2020-08-01
Series:Biomedicines
Subjects:
prostate cancer
Intracrine androgen synthesis
CYP17
genistein combined polysaccharide
Genistein
Online Access:https://www.mdpi.com/2227-9059/8/8/282

Internet

https://www.mdpi.com/2227-9059/8/8/282

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