BART inhibits pancreatic cancer cell invasion by PKCα inactivation through binding to ANX7.

A novel function for the binder of Arl two (BART) molecule in pancreatic cancer cells is reported. BART inhibits invasiveness of pancreatic cancer cells through binding to a Ca(2+)-dependent, phosphorylated, guanosine triphosphatase (GTPase) membrane fusion protein, annexin7 (ANX7). A tumor suppress...

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Bibliographic Details
Main Authors: Keisuke Taniuchi, Kunihiko Yokotani, Toshiji Saibara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22532868/?tool=EBI