The protein partners of GTP cyclohydrolase I in rat organs.

The protein partners of GTP cyclohydrolase I in rat organs.

GTP cyclohydrolase I (GCH1) is the rate-limiting enzyme for tetrahydrobiopterin biosynthesis and has been shown to be a promising therapeutic target in ischemic heart disease, hypertension, atherosclerosis and diabetes. The endogenous GCH1-interacting partners have not been identified. Here, we dete...

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Bibliographic Details
Main Authors: Jianhai Du, Ru-Jeng Teng, Matt Lawrence, Tongju Guan, Hao Xu, Ying Ge, Yang Shi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3313957?pdf=render

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http://europepmc.org/articles/PMC3313957?pdf=render

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