Usefulness of CD4+CD45RBhigh CD25− Cell–Transferred SCID Mice for Preclinical Evaluation of Drugs for Inflammatory Bowel Disease
Abstract.: Mouse colitis induced by transfer of CD4+CD45RBhigh CD25− cells share many pathological features with human inflammatory bowel disease (IBD). However, there is little known about how mouse colitis responds to drugs used for IBD treatment. To address this issue, we have investigated the ef...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2009-01-01
|
| Series: | Journal of Pharmacological Sciences |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1347861319311922 |