Human Pluripotent Stem Cell Differentiation into Functional Epicardial Progenitor Cells

Summary: Human pluripotent stem cells (hPSCs) are widely used to study cardiovascular cell differentiation and function. Here, we induced differentiation of hPSCs (both embryonic and induced) to proepicardial/epicardial progenitor cells that cover the heart during development. Addition of retinoic a...

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Bibliographic Details
Main Authors: Juan Antonio Guadix, Valeria V. Orlova, Elisa Giacomelli, Milena Bellin, Marcelo C. Ribeiro, Christine L. Mummery, José M. Pérez-Pomares, Robert Passier
Format: Article
Language:English
Published: Elsevier 2017-12-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671117304782