Renin-Angiotensin System Inhibitors Reduce Serum Asymmetric Dimethylarginine Levels and Oxidative Stress in Normotensive Patients with Chronic Kidney Disease

Background/Aims: The purpose of our study was to elucidate the relationship between asymmetric dimethylarginine (ADMA) and intrarenal lesions and to determine the effect of renin-angiotensin system inhibitors (RAS-Is) on serum ADMA levels, nitric oxide (NO) synthesis and oxidative stress in normoten...

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Bibliographic Details
Main Authors: Hideki Fujii, Keiji Kono, Kentaro Nakai, Shunsuke Goto, Riko Kitazawa, Masafumi Fukagawa, Shinichi Nishi
Format: Article
Language:English
Published: Karger Publishers 2014-02-01
Series:Nephron Extra
Subjects:
Online Access:http://www.karger.com/Article/FullText/358886