VEGF receptor blockade markedly reduces retinal microglia/macrophage infiltration into laser-induced CNV.

Although blocking VEGF has a positive effect in wet age-related macular degeneration (AMD), the effect of blocking its receptors remains unclear. This was an investigation of the effect of VEGF receptor (VEGFR) 1 and/or 2 blockade on retinal microglia/macrophage infiltration in laser-induced choroid...

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Bibliographic Details
Main Authors: Hu Huang, Rachel Parlier, Ji-Kui Shen, Gerard A Lutty, Stanley A Vinores
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23977149/pdf/?tool=EBI