Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres

Gossypol Suppresses Growth of Temozolomide-Resistant Glioblastoma Tumor Spheres

Temozolomide is the current first-line treatment for glioblastoma patients but, because many patients are resistant to it, there is an urgent need to develop antitumor agents to treat temozolomide-resistant glioblastoma. Gossypol, a natural polyphenolic compound, has been studied as a monotherapy or...

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Bibliographic Details
Main Authors: Hee Yeon Kim, Byung Il Lee, Ji Hoon Jeon, Dong Keon Kim, Seok-Gu Kang, Jin-Kyoung Shim, Soo Youl Kim, Sang Won Kang, Hyonchol Jang
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biomolecules
Subjects:
bcl2
dehydrogenase
glioblastoma
gossypol
temozolomide resistance
Online Access:https://www.mdpi.com/2218-273X/9/10/595

Internet

https://www.mdpi.com/2218-273X/9/10/595

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