Effects of sodium nitroprusside in the prevention of schizophrenia-like symptoms induced by ketamine – A translational double-blind study

Abstract Background: Recent evidence has shown improvements in schizophrenia symptoms after the infusion of sodium nitroprusside (SNP), a nitric oxide (NO) donor. In the rat model of schizophrenia using ketamine injection, pretreatment with SNP seems to prevent behavioral changes associated with po...

Full description

Bibliographic Details
Main Authors: Tatiana M. N. Rezende, João Paulo Maia-de-Oliveira, Ludmyla Kandratavicius, João Paulo Machado-de-Sousa, João Abrão, Daniel Almeida Prado, Rodrigo A. Bressan, Acioly L. T. Lacerda, Antonio W. Zuardi, Glen B. Baker, Serdar M. Dursun, Jaime E. C. Hallak
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Archives of Clinical Psychiatry
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0101-60832017000600149&lng=en&tlng=en