The mature EV71 virion induced a broadly cross-neutralizing VP1 antibody against subtypes of the EV71 virus.

Enterovirus 71 (EV71) has emerged as a neurological virus causing life-threatening diseases in young children and infants. Although EV71 vaccines in development have presented promising results in several clinical trials, the identified key antigen for improving the broad protective efficacy of EV71...

Full description

Bibliographic Details
Main Authors: Chia-Ying Wu, Shu-Ling Yu, Yung-Tsung Chen, Yi-Hsuan Chen, Pei-Wen Hsiao, Yen-Hung Chow, Juine-Ruey Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0210553