A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

A broadly neutralizing monoclonal antibody induces broad protection against heterogeneous PRRSV strains in piglets

Abstract Neutralizing antibodies (NAbs) have attracted attention as tools for achieving PRRSV control and prevention, but viral antigenic variation undermines the abilities of NAbs elicited by attenuated PRRSV vaccines to confer full protection against heterogeneous PRRSV field isolates. As demonstr...

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Bibliographic Details
Main Authors: Zhigang Zhang, Tianshu Zhai, Mingshuo Li, Kun Zhang, Jingrui Li, Xu Zheng, Chaonan Tian, Rui Chen, Jianhui Dong, En-Min Zhou, Yuchen Nan, Chunyan Wu
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Veterinary Research
Subjects:
PRRSV
Monoclonal antibody
Broad neutralizing antibodies
Anti-PRRSV therapy
Transcriptome profiling
Online Access:https://doi.org/10.1186/s13567-021-00914-0

Internet

https://doi.org/10.1186/s13567-021-00914-0

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