Prolongation of Islet Allograft Survival in Mice by Combined Treatment with Pravastatin and Low-Dose Cyclosporine
Pravastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase inhibitor, is known to have suppressive effects on immune and inflammatory cells. We have previously shown in mice and dogs that this agent prevents primary nonfunction of islet iso- and autografts by reducing inflammation at t...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2001-10-01
|
| Series: | Cell Transplantation |
| Online Access: | https://doi.org/10.3727/000000001783986396 |