Biochemical characterization of novel retroviral integrase proteins.

Integrase is an essential retroviral enzyme, catalyzing the stable integration of reverse transcribed DNA into cellular DNA. Several aspects of the integration mechanism, including the length of host DNA sequence duplication flanking the integrated provirus, which can be from 4 to 6 bp, and the nucl...

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Bibliographic Details
Main Authors: Allison Ballandras-Colas, Hema Naraharisetty, Xiang Li, Erik Serrao, Alan Engelman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790719?pdf=render