Pathophysiology of Mitochondrial Dysfunction in Human Spermatozoa: Focus on Energetic Metabolism, Oxidative Stress and Apoptosis

Pathophysiology of Mitochondrial Dysfunction in Human Spermatozoa: Focus on Energetic Metabolism, Oxidative Stress and Apoptosis

The dogma of mitochondria as the major source of energy in supporting sperm motility should be critically reconsidered in the light of several experimental data pointing to a major role of glycolysis in mammalian spermatozoa. In this light, the reported positive correlation between the mitochondrial...

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Bibliographic Details
Main Authors: Chiara Castellini, Settimio D’Andrea, Giuliana Cordeschi, Maria Totaro, Antonio Parisi, Giovanna Di Emidio, Carla Tatone, Sandro Francavilla, Arcangelo Barbonetti
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antioxidants
Subjects:
adenosine trisphosphate (ATP)
apoptosis
glycolysis
mitochondria
oxidative phosphorylation
spermatozoa
Online Access:https://www.mdpi.com/2076-3921/10/5/695

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https://www.mdpi.com/2076-3921/10/5/695

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