Indoxyl Sulfate, Not P-Cresyl Sulfate, is Associated with Advanced Glycation end Products in Patients on Long-Term Hemodialysis
Background/Aims: Advanced glycation end products (AGEs) are pro-inflammatory and pro-oxidative compounds that play a critical role in endothelial dysfunction and atherosclerosis. Protein-bound uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), inhibit endothelial function. We explored t...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Karger Publishers
2015-03-01
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Series: | Kidney & Blood Pressure Research |
Subjects: | |
Online Access: | http://www.karger.com/Article/FullText/368488 |