Indoxyl Sulfate, Not P-Cresyl Sulfate, is Associated with Advanced Glycation end Products in Patients on Long-Term Hemodialysis

Background/Aims: Advanced glycation end products (AGEs) are pro-inflammatory and pro-oxidative compounds that play a critical role in endothelial dysfunction and atherosclerosis. Protein-bound uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), inhibit endothelial function. We explored t...

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Bibliographic Details
Main Authors: Cheng-Jui Lin, Jackson Lin, Chi-Feng Pan, Chih-Kuang Chuang, Hsuan-Liang Liu, Fang-Ju Sun, Tuan-Jen Wang, Han-Hsiang Chen, Chih-Jen Wu
Format: Article
Language:English
Published: Karger Publishers 2015-03-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/368488