Long standing eculizumab treatment without anticoagulant therapy in high-risk thrombogenic paroxysmal nocturnal hemoglobinuria

Long standing eculizumab treatment without anticoagulant therapy in high-risk thrombogenic paroxysmal nocturnal hemoglobinuria

Paroxysmal nocturnal hemoglobinuria (PNH) is an ultra-orphan disease affecting all hematopoietic cell types. The abnormality of red blood cells in this disease predisposes to intravascular complement-mediated hemolysis. Eculizumab is an orphan drug used to treat this rare disease. Thrombosis is the...

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Bibliographic Details
Main Authors: Hassan A. Al-Jafar, Salma M. AlDallal, Haifa A. Askar, Ali M. Aljeraiwi, Ahmad Al-Alansari
Format: Article
Language:English
Published: PAGEPress Publications 2015-09-01
Series:Hematology Reports
Subjects:
aroxysmal nocturnal hemoglobinuria
eculizumab
thrombosis
orphan
anticoagulant
Online Access:http://www.pagepress.org/journals/index.php/hr/article/view/5927

Internet

http://www.pagepress.org/journals/index.php/hr/article/view/5927

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