Specific phosphorylation of histone demethylase KDM3A determines target gene expression in response to heat shock.
Histone lysine (K) residues, which are modified by methyl- and acetyl-transferases, diversely regulate RNA synthesis. Unlike the ubiquitously activating effect of histone K acetylation, the effects of histone K methylation vary with the number of methyl groups added and with the position of these gr...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2014-12-01
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| Series: | PLoS Biology |
| Online Access: | http://europepmc.org/articles/PMC4275180?pdf=render |