Licensed and unlicensed NK cells: Differential roles in cancer and viral control

NK cells are known for their well characterized ability to control viral infections and eliminate tumor cells. Through their repertoire of activating and inhibitory receptors, NK cells are able to survey different potential target cells for various surface markers, such as MHC-I—which signals to the...

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Bibliographic Details
Main Authors: Megan M Tu, Ahmad Bakur Mahmoud, Andrew P Makrigiannis
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00166/full