Licensed and unlicensed NK cells: Differential roles in cancer and viral control
NK cells are known for their well characterized ability to control viral infections and eliminate tumor cells. Through their repertoire of activating and inhibitory receptors, NK cells are able to survey different potential target cells for various surface markers, such as MHC-I—which signals to the...
Main Authors: | Megan M Tu, Ahmad Bakur Mahmoud, Andrew P Makrigiannis |
---|---|
Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2016-05-01
|
Series: | Frontiers in Immunology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00166/full |
Similar Items
-
Influenza Virus Evades NK Cell Responses by Enhancing Ly49:MHC-I Interactions
by: Mahmoud, Ahmad Bakur
Published: (2016) -
ADAPTATIONS OF NATURAL KILLER CELLS TO SELF-MHC CLASS I
by: Stéphanie eBessoles, et al.
Published: (2014-07-01) -
Ly49 receptors: Innate and adaptive immune paradigms
by: Mir Munir A Rahim, et al.
Published: (2014-04-01) -
The interaction with H-2Dd in cis is associated with a conformational change in the Ly49A NK cell receptor
by: Jonathan eBack, et al.
Published: (2011-10-01) -
Inhibitory Receptor Crosslinking Quantitatively Dampens Calcium Flux Induced by Activating Receptor Triggering in NK Cells
by: Sridharan Ganesan, et al.
Published: (2019-01-01)