The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

The AAA protein Msp1 mediates clearance of excess tail-anchored proteins from the peroxisomal membrane

Msp1 is a conserved AAA ATPase in budding yeast localized to mitochondria where it prevents accumulation of mistargeted tail-anchored (TA) proteins, including the peroxisomal TA protein Pex15. Msp1 also resides on peroxisomes but it remains unknown how native TA proteins on mitochondria and peroxiso...

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Bibliographic Details
Main Authors: Nicholas R Weir, Roarke A Kamber, James S Martenson, Vladimir Denic
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-09-01
Series:eLife
Subjects:
quality control
AAA ATPase
tail-anchored protein
mitochondria
peroxisome
Online Access:https://elifesciences.org/articles/28507

Internet

https://elifesciences.org/articles/28507

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