Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.

Deleted in liver cancer 2 (DLC2) was dispensable for development and its deficiency did not aggravate hepatocarcinogenesis.

DLC2 (deleted in liver cancer 2), a Rho GTPase-activating protein, was previously shown to be underexpressed in human hepatocellular carcinoma and has tumor suppressor functions in cell culture models. We generated DLC2-deficient mice to investigate the tumor suppressor role of DLC2 in hepatocarcino...

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Bibliographic Details
Main Authors: Tai On Yau, Thomas Ho Yin Leung, Sandra Lam, Oi Fung Cheung, Edmund Kwok Kwan Tung, Pek Lan Khong, Amy Lam, Sookja Chung, Irene Oi Lin Ng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2718616?pdf=render

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http://europepmc.org/articles/PMC2718616?pdf=render

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