Oxymatrine protects against l-arginine-induced acute pancreatitis and intestine injury involving Th1/Th17 cytokines and MAPK/NF-κB signalling

Oxymatrine protects against l-arginine-induced acute pancreatitis and intestine injury involving Th1/Th17 cytokines and MAPK/NF-κB signalling

Context: Oxymatrine (OMT) has various pharmacological effects, including immune reaction regulation, anti-inflammation and anti-hypersensitive reaction. Objective: This is the first report to investigate the molecular mechanism of OMT function in l-arginine (Arg)-induced acute pancreatitis (AP) invo...

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Bibliographic Details
Main Authors: Zhiqiang Zhang, Qingfeng Liu, Hui Zang, Qingliang Shao, Tian Sun
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Pharmaceutical Biology
Subjects:
intestinal barrier
inflammation
il17
ror-γt
t-bet
erk
p38
Online Access:http://dx.doi.org/10.1080/13880209.2019.1657906

Internet

http://dx.doi.org/10.1080/13880209.2019.1657906

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