Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone

Role of differentially expressed microRNA-139-5p in the regulation of phenotypic internal anal sphincter smooth muscle tone

Abstract The present study focused on the role of microRNA-139-5p (miRNA-139-5p) in the regulation of basal tone in internal anal sphincter (IAS). Applying genome-wide miRNA microarrays on the phenotypically distinct smooth muscle cells (SMCs) within the rat anorectrum, we identified miRNA-139-5p as...

Full description

Bibliographic Details
Main Authors: Jagmohan Singh, Ipsita Mohanty, Sankar Addya, Benjamin Phillips, Hwan Mee Yong, Steven S. An, Raymond B. Penn, Satish Rattan
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01550-5

Internet

https://doi.org/10.1038/s41598-017-01550-5

Similar Items