Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis

Blood eosinophil count, a marker of inhaled corticosteroid effectiveness in preventing COPD exacerbations in post-hoc RCT and observational studies: systematic review and meta-analysis

Abstract Background Blood eosinophil count has been proposed as a predictor of response to inhaled corticosteroid (ICS) in the prevention of acute exacerbations of COPD. An optimal threshold of blood eosinophil count for prescribing ICS has not been agreed. Doubt has been cast on the role by observa...

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Bibliographic Details
Main Authors: Timothy H. Harries, Victoria Rowland, Christopher J. Corrigan, Iain J. Marshall, Lucy McDonnell, Vibhore Prasad, Peter Schofield, David Armstrong, Patrick White
Format: Article
Language:English
Published: BMC 2020-01-01
Series:Respiratory Research
Subjects:
Pulmonary disease, chronic obstructive
Eosinophils
Inhaled corticosteroids
Randomised controlled trials
Observational studies
Online Access:https://doi.org/10.1186/s12931-019-1268-7

Internet

https://doi.org/10.1186/s12931-019-1268-7

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