Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients

Host Genetics, Innate Immune Responses, and Cellular Death Pathways in Poliomyelitis Patients

PurposePoliovirus (PV) is one of the most studied viruses. Despite efforts to understand PV infection within the host, fundamental questions remain unanswered. These include the mechanisms determining the progression to viremia, the pathogenesis of neuronal infection and paralysis in only a minority...

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Bibliographic Details
Main Authors: Nanna-Sophie B. Andersen, Simon M. Larsen, Sara K. Nissen, Sofie E. Jørgensen, Maibritt Mardahl, Mette Christiansen, Lise Kay, Trine H. Mogensen
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
poliovirus
paralytic poliomyelitis
innate immunity
interferon
autophagy
apoptosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01495/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.01495/full

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