A modeling strategy for G-protein coupled receptors

A modeling strategy for G-protein coupled receptors

Cell responses can be triggered via G-protein coupled receptors (GPCRs) that interact with small molecules, peptides or proteins and transmit the signal over the membrane via structural changes to activate intracellular pathways. GPCRs are characterized by a rather low sequence similarity and exhibi...

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Bibliographic Details
Main Authors: Anna Kahler, Heinrich Sticht
Format: Article
Language:English
Published: AIMS Press 2016-03-01
Series:AIMS Biophysics
Subjects:
GPCR
MD simulation
homology modeling
HCMV
transmembrane helix
Online Access:http://www.aimspress.com/biophysics/article/694/fulltext.html

Internet

http://www.aimspress.com/biophysics/article/694/fulltext.html

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