Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis

Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis

Radiation induced lung fibrosis (RILF) is a common late complication after radiotherapy without effective treatment. Thyroid hormone (TH) is known to reverse bleomycin-induced pulmonary fibrosis in recent study. We therefore sought to examine TH effect in RILF. Aerosolized TH delivery prevented pulm...

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Bibliographic Details
Main Authors: Long Li, Xiaoqi Nie, Minxiao Yi, Wan Qin, Fang Li, Bili Wu, Xianglin Yuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Oncology
Subjects:
radiation induced lung fibrosis
aerosolized
thyroid hormone
TGF-β1
macrophage
hypothyroidism
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.528686/full

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https://www.frontiersin.org/article/10.3389/fonc.2020.528686/full

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