Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4<sup>+</sup> T Cells Associated with Poor Disease-Specific Survival

Transcriptome of Tumor-Infiltrating T Cells in Colorectal Cancer Patients Uncovered a Unique Gene Signature in CD4<sup>+</sup> T Cells Associated with Poor Disease-Specific Survival

Colorectal cancer (CRC) is influenced by infiltration of immune cell populations in the tumor microenvironment. While elevated levels of cytotoxic T cells are associated with improved prognosis, limited studies have reported associations between CD4<sup>+</sup> T cells and disease outcom...

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Bibliographic Details
Main Authors: Salman M. Toor, Varun Sasidharan Nair, Reem Saleh, Rowaida Z. Taha, Khaled Murshed, Mahmood Al-Dhaheri, Mahwish Khawar, Ayman A. Ahmed, Mohamed A. Kurer, Mohamed Abu Nada, Eyad Elkord
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Vaccines
Subjects:
colorectal cancer
tumor microenvironment
T cells
transcriptomics
Online Access:https://www.mdpi.com/2076-393X/9/4/334

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